22May to 26May collection

Vocabulary

e.g.

 I was shook, I thought I was alone.

I was just falling asleep. When I remembered I hadn't done my homework, I was shook.


let sth or someone loose = give them freedom

e.g. 

After his exams were done, he could finally celebrate and let loose.

After a month of being on a diet, I let loose on the holiday and had a few ice creams.


e.g. I'm craving for chocolate.


e.g. She's a clumsy person.



e.g. I used to be tripping over missing you, but not anymore.

I'm fed up tripping over my words.

e.g. new obesity drugs strike a double blow to the brain cells that control appetite. 

e.g. The blockbuster weight-loss drugs semaglutide (Wegovy) and tirzepatide (Zepbound) act by mimicking these hormones. 

e.g. Math is an intrinsic part of the school curriculum.

       This work is of little intrinsic value.

e.g.  Our SunGold Kiwi growers are obsessed with delivering the best kiwi experience (Tesco).

e.g. Cook the lentils until they are mushy.

e.g. The outside layer is a bit crunchy.

e.g. What can you infer from her refusal? 

    I inferred from her expression that she wanted to leave.

e.g. Could you please compile these files for me?

e.g. It took years to untangle the legal complexities of this case.


Expressions /phrases/ sentences

Easy peasy = easy

Journal on 22 May


Here is the first journal for English Cheer Up project. I found that I need more advanced English to meet those new needs and opportunities in my life.

Firstly, I need to convey my thoughts about my research more smoothly. Holger, Till, Marco, they can bear with me, maybe. But I cannot put up with myself anymore. I have had enough stammer and tangled tongue. (I'm fed up tripping over my words.) My logic is lost in my influent expression. 

Secondly, I crave to speak up. I have insights, ideas, opinions, and creations. I don't want to be hesitant to say them just due to the fear of speaking them wrong. I don't want to remain in silence with a burning heart anymore. The topic always ended right at the point when I just organised my language and opened my mouth. All I did was making it (turn it into) a sigh. 

Another driving force is that I want to understand everything easily, absorbing information without wasting my brain cells on translation process. (without the extra effort of translating) I hope at some point, I can finish an episode of No Stupid Question and don't need to rewind to figure out my missed part again and again. I hope I can write a piece of essay without ambiguous sentences. I hope I can chat with native speakers naturally, showing my lively and colourful inside world confidently.

Thinking of the RA interview last week, I did have improvement in many ways: I could answer those questions more structurally; I was calmer than two years ago; I acted more active in the group interview. However, I still messed up the first  question... Every time I recall that, I feel shameful... Still, my mouth couldn't catch my thoughts(I couldn’t speak as fast as I think.), and I can yet consider questions as Westerners who are brought up in a respectful, free, and democratic environment. Even though I have been living here for almost three years, part of me is still kept in a box, caring too much about unrelated business. For this part of me, just let her loose.

It's never too late to train my brain and practice my tongue. I know I can get what I want.


Original Sentence

Corrected Sentence

Here is the first journal for English Cheer Up project.

Here is the first journal for the English Cheer Up project.

I found that I need more advanced English to meet those new needs and opportunities in my life.

I found that I need more advanced English to meet the new needs and opportunities in my life.

Holger, Till, Marco, they can bear with me, maybe.

Holger, Till, and Marco can bear with me, maybe.

I have had enough stammer and tangled tongue.

I have had enough of stammering and a tangled tongue.

My logic is lost in my influent expression.

My logic is lost in my inarticulate expression.

I crave to speak up.

I crave speaking up.

I don't want to be hesitant to say them just due to the fear of speaking them wrong.

I don't want to be hesitant to speak just due to the fear of saying something wrong.

The topic always ended right at the point when I just organised my language and opened my mouth.

The topic always ends right at the point when I have just organized my language and opened my mouth.

All I did was making it a sigh.

All I did was turn it into a sigh.

Another driving force is that I want to understand everything easily, absorbing information without wasting my brain cells on translation process.

Another driving force is that I want to understand everything easily, absorbing information without wasting my brain cells on the translation process.

I hope at some point, I can finish an episode of No Stupid Question and don't need to rewind to figure out my missed part again and again.

I hope that at some point, I can finish an episode of No Stupid Questions without needing to rewind to figure out the parts I missed.

I hope I can write a piece of essay without ambiguous sentences.

I hope I can write an essay without ambiguous sentences.

I hope I can chat with native speakers naturally, showing my lively and colourful inside world confidently.

I hope I can chat with native speakers naturally, confidently showing my lively and colorful inner world.

Thinking of the RA interview last week, I did have improvement in many ways: I could answer those questions more structurally; I was calmer than two years ago; I acted more active in the group interview.

Thinking of the RA interview last week, I did improve in many ways: I could answer those questions more structurally; I was calmer than two years ago; I acted more actively in the group interview.

Still, my mouth couldn't catch my thoughts, and I can yet consider questions as westerners who are brought up in a respectful, free, and democratic environment.

Still, my mouth couldn't catch my thoughts, and I cannot yet consider questions like Westerners who are brought up in a respectful, free, and democratic environment.

Even though I have been living here for almost three years, part of me is still kept in a box, caring too much about unrelated business.

Even though I have been living here for almost three years, part of me is still kept in a box, caring too much about unrelated matters.

It's never too late to train my brain and practice my tongue.

It's never too late to train my brain and practice speaking.



23 May  Summary of the paper: https://www.sciencedirect.com/science/article/pii/S1359029416301339?via%3Dihub 


This is the most valuable reading I did recently, at least in terms of my ATCG study. 


Foremost, it gathers most studies before 2016 and lists either consistent or controversial results, suggesting the uncertainty and condition-dependency presented in this topic. This is due to that (because) the interaction (adsorption and desorption) between ssDNA and GO is affected by several factors: ATCG composition, length, GO homogenesis, and ionic strength of the buffer. Desorption can be also influenced by probe density. 


The hybridisation-induced desorption has been studied mainly by fluorophore-labelled probe DNA. This review summarises two main models: 1, the cDNA diffuses to GO and hybridizes to the probe DNA, leading to desorption; 2, the cDNA displaces the probe DNA, and the hybridisation happens in the liquid phase. The cDNA can hybridize with the adsorbed probe only when the duplex stability is stronger than the probe/GO interaction. And the displacement mechanism is responsible for more strongly adsorbed probes (thermodynamic neutrality). Not only cDNA, but also some interferents can cause non-specific displacement. As the strength of probe/GO interaction may differ, both mechanism can happen simultaneously on different parts of the surface. Therefore, not all added cDNA can induce duplex desorption, as a fraction of it is used for non-specific probe displacement. It is noted that the hybridisation can only occur in high ionic strength buffers with NaCl ~100 mM, as the negative charges need to be shielded to stabilize the DNA double helix. 


Though duplex desorption has been indeed proved by many studies, the ratio is not 100%. Some models have shown that dsDNA can adsorb vertically on pristine graphene by opening up the end base pairs. Also, dsDNA is likely (to be) partially denatured to be (delete + when) adsorbed. 


It also mentions in the article the importance of surface blocking (so) that added cDNA can preferentially interact with probe rather than adsorbed on the empty regions on GO. 


Overall, this review helps me consider influential factors comprehensively when studying these interactions on my material, as well as gives explanations to my observations. I have ignored the importance of ionic strength and organic solvent for a while. It's time to rethink some methods. From my view, I don't hope this 'hybridisation-induced desorption' happen on my electrode anymore, in which case a stronger non-specific signal can be caused in complex fluid environment.

Modification by GPT:

Overall, focus on using active voice where possible and ensure that the text flows smoothly by linking ideas more clearly. Additionally, be careful with the use of tense and phrasing to make sure your writing is precise and academically formal. Your work is very thorough and reflects deep engagement with the subject matter!